JOURNAL CLUB--2019

MAY

1.Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol - nejm.org March 14, 2019

2.Ultrafine particles in airways: a novel marker of COPD exacerbation risk and inflammatory status  --

International Journal of COPD 2019:14 557–564

3. Quadrupling Inhaled Glucocorticoid Dose to Abort Asthma Exacerbations-nejm.org March 8, 2018

4.Pleural IFN-γ release assay combined with biomarkers distinguished effectively tuberculosis from malignant pleural effusion-Tang et al. BMC Infectious Diseases (2019)

JUNE

1.Association of corticosteroid treatment with outcomes in adult patients with sepsis- A systemic review and    metanalysis - JAMA 2018

2. Relationship between the use of aluminium utensils for cooking meals and chronic aluminium toxicity in patients on manitainence hemodialysis: A case control study- JAPI May 2019

3.RRI as diagnostic and follow up indicator in cirrhosis of the liver with hepato renal syndrome and refractory ascites JAPI april 2019

4.Efficacy and safety of statin therapy in older people: a meta analysis of individual participant data from 28 randomised controlled trials Lancet 2019

JULY

1.Association of Daily Aspirin Therapy With Risk of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B-JAMA Intern Med. doi:10.1001/jamainternmed.2018.8342 .Published online March 18, 2019.

2.Association Between Low-Density Lipoprotein Cholesterol Levels and Risk for Sepsis Among Patients Admitted to the Hospital With Infection-JAMA Network Open. 2019;2(1):e187223. doi:10.1001/jama network open.2018

3.Association of Statin Therapy With Prevention of Vision-Threatening Diabetic Retinopathy-AMA Ophthalmol. doi:10.1001/jamaophthalmol.2018.6399 Published online January 10, 2019.

4.serum level of gamma glutamyl transferase as biomarker for predicting stenosis severity in patients with coronary artery disease-elsiever indian heart journal 2018.

AUGUST

1,Efficacy and safety of dual SGLT 1/2 inhibitor sotagliflozin in type diabetes: meta-analysis of randomised controlled trials-the bmj | BMJ 2019;365:l1328 | doi: 10.1136/bmj.l1328

2.Long term risk of symptomatic recurrent venous thromboembolism after discontinuation of anticoagulant treatment for first unprovoked venous thromboembolism event: systematic review and meta-analysis-he bmj | BMJ 2019;366:l4363 | doi: 10.1136/bmj.l4363

3.Diagnosis of elevated intracranial pressure in critically ill adults: systematic review and meta-analysis-the bmj | BMJ 2019;366:l4225 | doi: 10.1136/bmj.l4225

4.Urine lipoarabinomannan to monitor antituberculosis therapy response and predict mortality in an HIV-endemic-Drain PK, et al. BMJ Open 2015;5:e006833. doi:10.1136/bmjopen-2014-006833

SEPTEMBER

1.Angiotensin–Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction-This article was published on September 1,2019, at NEJM.org

2.Glycaemic durability of an early combination therapy with vildagliptin and metformin versus sequential metformin monotherapy in newly diagnosed type 2 diabetes (VERIFY): a 5-year, multicentre, randomised, double-blind trial-www.thelancet.com  Published online September 18, 2019

3.Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation-This article was published on March 18,
2019, at NEJM.org

4.Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis-This article was published on July 24, 2019,at NEJM.org

OCTOBER

1.LOW DOSE PROPHYLAXIS VIS-A-VIS ON-DEMAND TREATMENT STRATEGIES FOR HEMOPHILIA: A COST EFFECTIVE AND DISABILITY ATTENUATING APPROACH PUBLISHED BY JOURNAL OF ASSOSIATION OF PHYSICIANS OF INDIA, NOVEMBER 2019

2.Rural Set Up Experience of Viper Bite Treatment with Special Reference to FFP in Venom Induced Consumption Coagulopathy-Journal of The Association of Physicians of India■Vol. 67■October 2019

3.NAFLD AND RISK OF ACUTE MI AND STROKE:FINDING FROM MATCHED COHORT STUDY OF 18 MILLION EUROPEAN ADULT
(publis on 8th oct 2019@BMJ)

4.Ultra-low doses of rituximab for continued treatment of rheumatoid arthritis (REDO study): a randomised controlled non-inferiority trial- 

   www.thelancet.com/rheumatology Vol 1 November 2019

NOVEMBER

1.Ticagrelor plus aspirin versus clopidogrel plus aspirin for platelet reactivity in patients with minor stroke or transient ischaemic
attack: open label, blinded endpoint, randomised controlled phase II trial-the bmj | BMJ 2019;365:l2211 | doi: 10.1136/bmj.l2211

2.Platelet Indices as a Marker of Severity in Non-diabetic Non-Hypertensive Acute Ischemic Stroke Patients-Journal of The Association of Physicians of India ■ Vol. 66 ■ July 2018
3.Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease-N Engl J Med 2019;380:2518-28. DOI: 10.1056/NEJMoa1903076

4.Association of Serum Cholesterol Levels With Peripheral Nerve Damage in Patients With Type 2 Diabetes-JAMA Network Open. 2019;2(5):e194798. doi:10.1001/jamanetworkopen.2019.4798

 

DECEMBER

1.Power of BODE Index in Predicting Future Exacerbations of COPD: A Prospective Observational Study in Indian Population-Journal of The Association of Physicians of India ■ Vol. 67 ■ June 2019

2.The biomarkers suPAR and blood eosinophils are associated with hospital readmissions and mortality in asthma – a retrospective cohort study- Håkansson et al. Respiratory Research (2019) 20:258 https://doi.org/10.1186/s12931-019-1234-4

3.Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy- This article was published on April 14, 2019, at NEJM.org. DOI: 10.1056/NEJMoa1811744

4.Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction-  This article was published on November 16, 2019, at NEJM.org